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A Transcriptively Active Complex of APP with Fe65 and Histone Acetyltransferase Tip60
Amyloid-β precursor protein (APP), a widely expressed cell-surface protein, is cleaved in the transmembrane region by γ-secretase.
Smartphone and medical related App use among medical students and junior doctors in the United K
Abstract Background Smartphone usage has spread to many settings including that of healthcare with numerous potential and realised ben
APP processing in Alzheimer's disease
AbstractAn important pathological feature of Alzheimer's disease (AD) is the presence of extracellular senile plaques in the brain. Se
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyl
We report duplication of the APP locus on chromosome 21 in five families with autosomal dominant early-onset Alzheimer disease (ADEOAD
Multi-Situated App Studies: Methods and Propositions
This article discusses methodological approaches to app studies, focusing on their embeddedness and situatedness within multiple infra
Real Challenges in Mobile App Development
Context: Mobile app development is a relatively new phenomenon that is increasing rapidly due to the ubiquity and popularity of smartp
A Smartphone App Reveals Erratic Diurnal Eating Patterns in Humans that Can Be Modulated for Hea
A diurnal rhythm of eating-fasting promotes health, but the eating pattern of humans is rarely assessed. Using a mobile app, we monito
Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP
JNPL3 transgenic mice expressing a mutant tau protein, which develop neurofibrillary tangles and progressive motor disturbance, were c
Acceptability of App-Based Contact Tracing for COVID-19: Cross-Country Survey Study.
BACKGROUND The COVID-19 pandemic is the greatest public health crisis of the last 100 years. Countries have responded with various lev
CoNet app: inference of biological association networks using Cytoscape.
Here we present the Cytoscape app version of our association network inference tool CoNet. Though CoNet was developed with microbial c
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